As a PDE-5 inhibitor, Cenforce prevents the PDE-5 group of hormones from working. This causes an increase in the level of cGMP, another hormone. Finally, the high levels of cGMP allow nitric oxide to work, which in turn cause
People with PH have narrow and constricted pulmonary arteries that connect the heart and lungs. Generic Sildenafil relieves PH by widening these arteries so that blood can flow more easily to the lungs. It also lowers blood pressure.
In a clinical trial in 2017, researchers randomly assigned 129 people with pulmonary arterial hypertension to one of three groups. Each group was prescribed 20 milligrams (mg), 100 milligrams (mg), and 120 milligrams (mg) of the pill three times a day.
When comparing the group that took 120 mg of this medication with the group that took 20 mg after 12 weeks of the study, the average distance people could walk in 6 minutes increased significantly. The 120 mg group showed the greatest increase in 6-minute walk distance at the end of the entire 24-week period. The 20 mg group showed the greatest increase in their 6-minute walk distance.
This research shows that the drug's effects can increase cardiovascular capabilities and endurance, which can improve a person's quality of life.
The Food and Drug Administration (FDA) recommends that adults with PH take 20 mg of Cenforce three times a day. Even doctors recommend that people taking the drug allow 4–6 hours between doses.
The drug label states that clinical trials have not shown that doses above 20 mg produce better results. However, a doctor may increase the dosage if the patient does not respond to the drug, to a maximum of 80 mg three times a day.
The severity of PA and a person's overall health may vary, so it is important to follow the doctor's advice and take the medication as prescribed.
The FDA does not recommend sildenafil for treating PH in children between the ages of 1 and 17.
Taking Cenforce for PH is generally safe for most people. Side effects can occur when taking any medication. These include:
In most cases, these side effects resolve on their own and are not necessarily a cause for concern. A person should seek medical attention if any of the side effects listed above are severe or persist.
You should seek immediate medical attention if you experience any of the following side effects:
When taking generic sildenafil for PH, interactions with other medications may occur. Some people, including pregnant women, should avoid taking Cenforce.
People with blood pressure below 90 millimeters of mercury should avoid taking sildenafil, according to the United Kingdom's National Institute for Health and Care Excellence (NICE).
A doctor can determine the appropriate dosage for a person based on their case and health condition before taking sildenafil for PH. There are also things a doctor can tell a patient about avoiding harmful interactions with other medications. In addition to grapefruit, they may recommend avoiding grapefruit juice and St. John's wort supplements as these can interact with medications like sildenafil and grapefruit.
Once a person has started taking sildenafil, they must inform their prescribing doctor as soon as possible after taking it if they experience any side effects. It may be necessary to adjust the dosage based on the test results.
Cenforce, better known as Viagra, can be used to treat PH. It dilates blood vessels so that blood can flow more easily to the lungs. A doctor will prescribe the appropriate dosage of Sildenafil if he or she considers it a safe treatment for people with PH. If you experience severe or persistent side effects, please inform your doctor.